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Last Updated: 07/05/2026
Inspiralis
Norwich
Founded 2006
DNA topoisomerase enzymes and substrates for drug discovery
Inspiralis is a John Innes Centre spinout supplying DNA-modifying enzymes, substrates and assay kits to pharmaceutical and academic researchers.
Its product range centres on topoisomerases, enzymes that regulate DNA topology and represent validated targets for antibiotic and anticancer drug development.
Alongside its product catalogue, Inspiralis offers contract screening services for compound libraries, mechanism of action studies, and cloning and expression of enzyme mutants, supporting preclinical programmes in anti-infective and oncology drug discovery.