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Last Updated: 05/06/2026

KalVista Pharmaceuticals

South West England
Founded 2011
Oral small molecule therapies for rare hereditary diseases

KalVista Pharmaceuticals is a biopharmaceutical company specialising in the discovery and commercialisation of oral small molecule protease inhibitors for rare diseases with significant unmet need.

The company's lead programme targets the kallikrein-kinin system and has produced an approved oral on-demand therapy for hereditary angioedema, a rare genetic disorder characterised by recurrent attacks of tissue swelling.

KalVista's drug discovery operations are based at its Salisbury laboratories, with commercial and clinical activities conducted globally.