Nucleome Therapeutics

Nucleome Therapeutics is a drug discovery company using 3D genome mapping to identify therapeutic targets encoded in the non-coding regions of the human genome.

Its platform integrates high-resolution chromatin conformation data with functional genomics and machine learning to link disease-associated genetic variants to causal genes in disease-relevant cell types, initially focusing on lymphocytes and autoimmune conditions.

The company uses this approach to identify genetically validated targets and companion patient stratification biomarkers for precision medicine programmes.