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Last Updated: 26/04/2026

Synteny

London
Founded 2021
Generative AI platform for TCR therapy design and immune repertoire analysis

Synteny Biotechnology is a biotechnology company developing a platform that combines high-throughput TCR-antigen data generation with generative AI to design precision T cell receptor therapies for cancer.

The platform addresses a critical bottleneck in the field, namely the scarcity of paired TCR-epitope interaction data, using protein language models to engineer TCRs with improved tumour specificity and reduced cross-reactivity.

The company applies this platform to an internal pipeline of TCR bispecific therapeutic candidates.

Company Notes