Company Directory

Automated bioreactor platform for cell and gene therapy manufacturing

microfluidX is a UK instruments company developing automated bioprocessing platforms for cell and gene therapy research and manufacturing. Its core product is a microfluidics-based bioreactor system designed for parallel cell culture process development and scalable cell expansion. The platform integrates online process analytical tools and data analytics and is intended to support the development and manufacture of autologous cell and gene therapies from research scale through to clinical and commercial production.

Human iPSC platform for neurodegenerative disease drug discovery

Talisman Therapeutics is a drug discovery company specialising in human induced pluripotent stem cell (iPSC) models of neurodegenerative disease. The company operates both an internal discovery pipeline, focused on Alzheimer's disease targets including lysosome biology, pathogenic protein reduction and microglial health, and an external collaboration programme. Talisman's iPSC-derived neural cell models are designed to improve the relevance and predictivity of early-stage compound screening.

Manufacturing and laboratory services for diagnostic innovators

Biofortuna is a contract development and manufacturing organisation providing assay development, lyophilisation, contract manufacturing, and controlled-environment storage services to the in vitro diagnostics, point-of-care, and life science sectors. Operating from ISO 13485-certified, ISO 17025-accredited, FDA-registered facilities in Deeside, the company develops and manufactures molecular assays including PCR and LAMP formats, as well as immunoassays, in lyophilised formats for ambient-temperature distribution. Additional services include cell line quality control testing, DNA extraction, biobanking, and stability storage.

Cell-based quality control materials for immunohistochemistry and ISH

HistoCyte Laboratories is a developer and manufacturer of cell-based quality control materials for immunohistochemistry and in situ hybridisation. Its products use proprietary cell line processing technology to produce formalin-fixed, paraffin-embedded control slides and blocks with reproducible, well-characterised biomarker expression for targets including HER2, ER and PR. The company serves diagnostic laboratories, biotech and pharmaceutical companies, and offers contract services including custom cell line development and biomarker assessment.

Mammalian recombinant protein production and cell line development services

Daresbury Proteins is a contract research organisation specialising in mammalian recombinant protein production and cell line development. Using proprietary expression vectors optimised for CHO-K1 and HEK293 systems, the company produces difficult-to-express proteins as research reagents and candidate targets for pharmaceutical and biotechnology clients. Services include stable pool and clonal cell line generation, with cell lines transferable to third-party cGMP manufacturing settings. Background intellectual property has been licensed to Thermo Fisher Scientific.

In vitro pharmacology CRO for preclinical drug discovery

Excellerate Bioscience is a contract research organisation specialising in molecular and cellular pharmacology for preclinical drug discovery. The company provides in vitro assay development, biochemical and cell-based screening, target validation, and compound profiling services to pharmaceutical companies, biotechnology firms, and academic institutions. Capabilities include GPCR kinetics, phenotypic screening, biophysical target engagement quantification, and bespoke cell line development. Excellerate supports projects from early target identification through to lead optimisation.

Bioprocess equipment supplier and maintenance services provider

BioProcess Engineering Services Limited (BPES) is a UK supplier of specialist equipment and support services to the biotechnology industry. It provides products and services across cell line development, upstream processing, and downstream processing workflows, serving pharmaceutical organisations, biotech companies, universities, and research charities. Its services include equipment maintenance, calibration, training, and application support. It holds BS EN ISO 9001:2015 accreditation and operates as an approved partner for specialist biotechnology equipment manufacturers.

Automated single-cell isolation and cloning instruments for cell biology

Iota Sciences is a developer of automated single-cell handling instruments and cell-line engineering services. The company's platform automates single-cell isolation and cloning in nanolitre volumes, supporting monoclonal cell line development with integrated viability monitoring and documentation. GRID Technology provides a microfluidic alternative to standard microtitre plates for cell culture workflows. Services include bespoke genome-engineering of induced pluripotent stem cell lines for researchers requiring precisely edited cell models.

Gene editing tools, cell lines and genomic reagents for life science research

Horizon Discovery is a Cambridge-based life sciences company supplying gene editing and gene modulation tools, services, and engineered cell lines to pharmaceutical, biotechnology, and academic customers. Its portfolio includes CRISPR and RNAi reagents, isogenic cell line pairs modelling disease-associated mutations, RNA synthesis, functional genomic screening services, and molecular reference standards for NGS-based diagnostics. The Cambridge site operates as a centre of excellence for genomic research within parent company Revvity.

High-throughput iPSC reprogramming and stem cell drug discovery services

Oxford StemTech is a contract research company providing induced pluripotent stem cell (iPSC) reprogramming and drug discovery services using its proprietary platform. The technology enables large-scale, cost-effective generation of patient-derived iPSC lines from blood or skin samples, supporting disease modelling, drug target discovery, and compound screening. Services include differentiation into disease-relevant cell types and cell-based assays for neurological and other complex conditions. The company also distributes iPSC lines under agreement with the University of Oxford.

Engineering biology CRDMO for pharma and industrial biotech

Ingenza is a contract research, development, and manufacturing organisation applying engineering biology to solve manufacturing challenges across pharmaceuticals and industrial biotechnology. The company provides strain and cell line engineering, fermentation, bioprocess development, and analytical services for biologics, small molecule APIs, and sustainably manufactured industrial products. Its facility near Edinburgh integrates molecular biology, scalable fermentation, and analytical chemistry. Ingenza serves pharma, chemicals, food, feed, and renewable fuels sectors, with customers across Europe and North America.

Human iPSC-derived cells and services for drug discovery research

Axol Bioscience is a biotechnology company manufacturing and supplying human induced pluripotent stem cell-derived cells and outsourced laboratory services for drug discovery and disease research. Its product range covers neuronal, cardiac, retinal, and dermal cell types derived from iPSCs sourced from patient and healthy donor lines. Services include iPSC reprogramming, gene editing, custom differentiation, cellular assays, and compound screening. Therapeutic focus areas span neuroscience, ophthalmology, cardiovascular disease, and dermatology.