Company Directory

AI-driven neural data platform for bioelectronic medicine

BIOS Health is a neural engineering company developing an AI-powered platform that reads and interprets peripheral nervous system signals in real time. Its technology links nerve activity to physiological conditions through the discovery of neural biomarkers, supporting the development of personalised neuromodulation therapies and neural digital therapeutics. BIOS serves pharmaceutical and medical device partners, academic research institutions, and NHS clinical programmes targeting cardiovascular, neurological, and autoimmune conditions.

Specialist CRO for ion channel screening and cardiac safety assessment

Metrion Biosciences is a contract research organisation specialising in preclinical ion channel biology, cardiac safety screening, and neuroscience drug discovery services. Founded in 2015 as a spin-out from Xention Limited, Metrion provides automated and manual patch clamp electrophysiology, GLP-compliant hERG testing, CiPA cardiac ion channel panel screening, and translational neuroscience assays. It serves pharmaceutical and biotechnology companies globally on a fee-for-service or collaborative basis from its laboratories at Granta Park, Cambridge.

AI-powered EEG platform for CNS clinical trials

Cumulus Neuroscience is a digital health software company providing an integrated brain monitoring and analytics platform for neuroscience clinical trials. Its platform combines a medical-grade EEG headset with machine learning analytics to generate objective, at-home physiological and cognitive biomarker data. Designed with ten leading pharmaceutical companies, the platform supports drug development across Alzheimer's disease, Parkinson's disease, depression, and schizophrenia.

Nonclinical safety toxicology and ion channel screening services

ApconiX is a nonclinical safety consultancy and ion channel laboratory supporting drug discovery and development programmes. The company provides project toxicology, DMPK support, target safety assessments, study outsourcing and monitoring, and specialist subject matter expertise across disciplines including safety pharmacology, genetic toxicology, reproductive toxicology and immunotoxicology. Its laboratory offers cardiac and CNS ion channel screening using automated and manual patch clamp platforms, including hERG, CiPA panel assays and its proprietary iSLA seizure liability assay.

Stem cell platform for precision psychiatry and drug discovery

MeOmics Precision Medicine is a biotechnology company developing a precision psychiatry platform that combines genomics, phenomics, and stem cell-based cellular assays to generate biomarkers for severe mental illness. Patient-derived neurons, stimulated via multi-electrode array recording, produce electrophysiological signatures used to stratify patients by biological subtype and predict drug response in vitro. The platform is designed to support pharmaceutical drug discovery for conditions including schizophrenia and bipolar disorder, reducing attrition in clinical development.

Affordable biochemicals, antibodies and reagents for life science research

Hello Bio is a Bristol-based manufacturer and supplier of biochemicals, antibodies, and reagents for life science research, offering validated tools at up to half the price of major suppliers. Products are manufactured in-house under ISO 9001 certification and span receptor ligands, enzyme inhibitors, ion channel modulators, epigenetic tools, stem cell reagents, fluorescent labels, and antibodies. The company has particular strength in neuroscience and chemogenetics tools and offers a custom synthesis service.

Closed-loop implantable neuromodulation for peripheral nervous system disorders

Amber Therapeutics is a medical technology company developing fully implantable, adaptive neuromodulation therapies for functional disorders of the peripheral nervous system. The closed-loop platform combines neural sensing, embedded signal classification, and adaptive stimulation to restore physiological function by responding in real time to a patient's own signals. Its lead programme targets mixed urinary incontinence in women and has demonstrated complete resolution of incontinence in early clinical studies.

Cardiac safety CRO using iPSC cardiomyocyte electrophysiology

Clyde Biosciences is a contract research organisation specialising in preclinical cardiovascular safety assessment using human iPSC-derived cardiomyocytes. Its proprietary platform measures membrane voltage, calcium transients and contractility in a single assay, providing high-resolution functional data on drug-induced cardiac effects. The company has been a core participant in the FDA-led CiPA initiative validating in vitro cardiomyocyte assays for pro-arrhythmic risk prediction. Clyde Biosciences serves pharmaceutical and biotechnology clients worldwide from facilities in Glasgow and Maryland, USA.

Fluorescence microscopy and electrophysiology instruments for biological research

Cairn Research is an independent, employee-owned manufacturer of scientific instruments for the biological sciences. The company designs and builds fluorescence imaging systems, light sources, image splitters, and integrated microscopy solutions for researchers using fluorescent indicators and proteins to study cellular physiology. Its product range also encompasses electrophysiology equipment, including a patch clamp amplifier, bioluminescence imaging enclosures, and flash photolysis systems. Cairn supplies standard products and bespoke custom systems to academic and research institutions worldwide.