Company Directory

Genomic diagnostics products for cytogenetics, oncology and rare disease

Oxford Gene Technology is a genomic diagnostics company developing and manufacturing hybridisation-based reagents and assays for clinical and research laboratories. Its product portfolio spans FISH probes, chromosomal microarrays and next-generation sequencing panels, enabling detection of chromosomal abnormalities and somatic mutations across haematological malignancies, solid tumours, cytogenetics and rare diseases. A FISH probe for KMT2A rearrangement in acute leukaemia received FDA De Novo classification as a companion diagnostic in 2024.

High-sensitivity lateral flow diagnostics for point-of-care testing

SwiftDx is a Cambridge-based diagnostics company developing a next generation of high-sensitivity lateral flow assays using proprietary eAMP (enhanced Amplification) and DNA detection technologies. Its platform enables detection of targets undetectable by conventional lateral flow tests, without requiring specialist equipment or laboratory facilities. The company's first commercial product is a rapid mycoplasma contamination detection kit for cell culture applications. Further products in development target HIV, dengue fever, hepatitis C, and prostate cancer.

Manufacturing and laboratory services for diagnostic innovators

Biofortuna is a contract development and manufacturing organisation providing assay development, lyophilisation, contract manufacturing, and controlled-environment storage services to the in vitro diagnostics, point-of-care, and life science sectors. Operating from ISO 13485-certified, ISO 17025-accredited, FDA-registered facilities in Deeside, the company develops and manufactures molecular assays including PCR and LAMP formats, as well as immunoassays, in lyophilised formats for ambient-temperature distribution. Additional services include cell line quality control testing, DNA extraction, biobanking, and stability storage.

Cell-based quality control materials for immunohistochemistry and ISH

HistoCyte Laboratories is a developer and manufacturer of cell-based quality control materials for immunohistochemistry and in situ hybridisation. Its products use proprietary cell line processing technology to produce formalin-fixed, paraffin-embedded control slides and blocks with reproducible, well-characterised biomarker expression for targets including HER2, ER and PR. The company serves diagnostic laboratories, biotech and pharmaceutical companies, and offers contract services including custom cell line development and biomarker assessment.

Infectious disease antigens and antibodies for diagnostics and research

The Native Antigen Company is a manufacturer of native and recombinant antigens, antibodies, and immunoassays for viral and bacterial infectious disease targets. Products are supplied to IVD manufacturers, pharmaceutical companies, and academic institutions for use in immunoassay development, serology, vaccine research, and quality control. Contract services include custom antigen manufacture, antibody generation, and assay development using a proprietary mammalian cell expression system for native-like protein production.

Molecular biology reagents and immunological raw materials for diagnostics

Meridian Bioscience's UK operation manufactures and supplies molecular biology reagents and immunological raw materials to diagnostic test developers, pharmaceutical companies, and research institutions worldwide. Products include ultra-pure nucleotides, DNA polymerases, PCR master mixes, purified antigens and antibodies, and isothermal amplification reagents used as critical components in the development and manufacture of molecular and immunological diagnostic tests. The London facility is one of the world's few producers of ultra-pure dNTPs.

Human biospecimen and disease-state plasma supplier

Logical Biological is a UK supplier of human biological materials including disease-state and normal-donor serum, plasma, swabs, tissues, PBMCs, and biofluids to IVD manufacturers and life science researchers worldwide. The company sources specimens through a global network of donor centres and blood banks across five continents, and provides customised materials including bulk engineered disease-state plasma, with capabilities in protein purification and sample processing. Customers include diagnostic test developers and IVD control manufacturers.

Single-workflow sequencing technology capturing genetic and epigenetic data

biomodal is a Cambridge-based life sciences technology company developing multiomics sequencing solutions that simultaneously capture genetic and epigenetic information from a single DNA sample. Its multiomics platform detects the canonical four DNA bases alongside 5-methylcytosine and 5-hydroxymethylcytosine modifications at single-base resolution, without requiring additional hardware or bisulfite treatment. The technology is compatible with existing sequencing infrastructure and targets applications in oncology, neurodegenerative disease research, and liquid biopsy diagnostics.

Specialist distributor of transplant diagnostics and molecular biology products

VH Bio is a specialist distributor of life science research and diagnostic products serving the United Kingdom and Republic of Ireland. The company focuses on four areas: transplant and HLA diagnostics, molecular biology, immunology, and cell biology. Its portfolio of approximately 10,000 products is sourced from global manufacturing partners, and VH Bio holds exclusive UK and ROI distribution rights for several suppliers. Products are dispatched from a dedicated warehouse and cold storage facility in Gateshead.

AI-powered infrared diagnostic test for breast cancer recurrence risk

Digistain is a biotechnology company developing MHRA-cleared diagnostic technology for predicting breast cancer recurrence risk. The platform uses infrared spectrometry to generate spectroscopic signatures from tumour biopsy tissue, with AI analysis producing a personalised prognostic score indicating the likelihood of disease recurrence over ten years. The technology is designed as a faster and lower-cost alternative to transcriptomic profiling methods, enabling patient stratification for adjuvant chemotherapy decisions.

In vitro diagnostic reagents, test kits and analysers for clinical laboratories

Fortress Diagnostics is a Northern Ireland-based manufacturer of in vitro diagnostic products, supplying clinical chemistry reagents, immunoassays, haematology reagents, haemostasis consumables, serology test kits, quality controls and calibrators, and diagnostic instrumentation to hospitals, blood banks, and research institutions across more than 100 countries. Operating from an ISO 13485-accredited facility at Antrim Technology Park, the company distributes through an established global network spanning five continents.

AI-powered rare disease case finding for primary care

Mendelian is a digital health software company developing AI-driven tools to support the earlier diagnosis of rare diseases in primary care. Its core product is a Class 1 regulated medical device that analyses electronic health records to identify patients whose symptom profiles are consistent with published diagnostic criteria for hundreds of rare conditions. The platform integrates with NHS clinical workflows and is used by GPs and primary care networks across the UK.