Company Directory

Clinical trial delivery for Alzheimer's and neurodegenerative disease

Scottish Brain Sciences is a contract research organisation building and operating clinical trial infrastructure for Alzheimer's disease and other neurodegenerative conditions. Working with pharmaceutical sponsors, it delivers trial screening, patient recruitment, and study conduct at dedicated clinical sites in Edinburgh and Aberdeen. Its capabilities span blood biomarker testing, neuroimaging, and cognitive assessment, enabling early detection and participant identification for disease-modifying therapy trials.

Real-world mental health and dementia data platform for drug development

Akrivia Health is a software company providing a real-world data and AI platform for neuroscience research and drug development. Its dataset of de-identified electronic health records from 6.3 million patients across 20 NHS Trusts covers mental health and dementia conditions, enriched through proprietary natural language processing. Commercial applications include health economics and outcomes research, clinical trial patient recruitment, pharmacovigilance, and drug discovery target identification.

Full service clinical trial and real-world evidence study management

O4 Research is a Belfast-based clinical research and site management organisation delivering full service and functional clinical trial services to pharmaceutical, biotechnology and consumer health companies across the UK, Ireland and Europe. The company specialises in late-phase clinical trials and non-interventional real-world evidence studies, offering services spanning concept development, study design, patient recruitment, clinical monitoring, regulatory submissions, medical writing, and data management.

Full-service CRO and pharmacovigilance services for biopharma

Ergomed is a global contract research organisation providing clinical development, pharmacovigilance, and regulatory compliance services to the pharmaceutical and biotechnology industries. Operating across more than 100 countries, the group manages Phase I to IV clinical trials with particular depth in oncology and rare disease programmes. Its portfolio of service brands includes Ergomed Clinical Research, PrimeVigilance for post-marketing drug safety, and ADAMAS Consulting for GxP auditing.

Global clinical research organisation providing consultant support for trials

Momentum Pharma is a company providing clinical trial consultants and functional service provider solutions to biotech, pharmaceutical and CRO clients globally. Operating as an alternative to traditional full-service CROs, it supplies embedded clinical research associates, programme managers and regulatory specialists on a flexible basis, with expertise spanning oncology, rare disease, haematology and neuroscience. The company operates across 45 countries and was recognised with a King's Award for Enterprise for international trade in 2022.

AI and photonics platform for personalised drug development

iLoF is a digital health company developing an AI-powered platform that uses proprietary photonics technology to generate optical fingerprints from blood samples, building a cloud-based library of biological profiles and biomarkers. The platform enables non-invasive patient stratification and personalised drug matching for clinical and preclinical trials, with an initial focus on Alzheimer's disease. Backed by Microsoft Ventures and Hamamatsu Ventures, iLoF operates from its R&D base at Discovery Park in Kent.

Global CRO delivering outsourced clinical development and safety services

ICON plc is a contract research organisation providing outsourced clinical development and commercialisation services to pharmaceutical, biotechnology, and medical device companies worldwide. The company supports the full product development lifecycle, from early-phase studies through to post-market safety monitoring. UK operations are based across sites in Swansea, Reading, and Livingston, with the Swansea hub specialising in clinical research services including pharmacovigilance.

Integrated formulation, GMP manufacture and Phase I clinical trials

BDD Pharma is a contract research and manufacturing organisation offering an integrated Lean Clinical Development pathway that combines formulation development, GMP manufacture, and Phase I clinical trials under one roof. The approach eliminates handoffs between separate service providers, reducing time to first-in-human data. BDD also develops its own drug delivery technologies, including a patented delayed-release oral tablet system. The company operates from two Glasgow sites and serves pharmaceutical clients globally.

Rare disease clinical trial specialist focused on patient-centred design

Actigen is a contract research organisation specialising in the design and delivery of clinical trials for rare and orphan diseases. Working in partnership with therapy developers and patient advocacy groups, the company employs inventive trial designs to accelerate development of medicines for conditions with significant unmet medical need. Its current programme is focused on clinical trials for mucopolysaccharidosis II in collaboration with an international biologics partner.

Specialist oncology CRO for early and late phase clinical trials

Theradex (Europe) Limited is the European arm of Theradex Oncology, a US-founded CRO with over 40 years specialising in oncology clinical development. The company provides full-service clinical trial management for pharma and biotech sponsors across early and late phase studies, with expertise in oncology, haematology, and immunology. Services include protocol design, regulatory support, site selection, monitoring, and data management. Theradex holds a long-standing contract with the US National Cancer Institute for clinical trials monitoring.

Specialist oncology clinical trial management for biotech and pharma

Karma Oncology is a specialist contract research organisation providing full-service and functional clinical trial management to biotechnology and pharmaceutical companies in oncology. Operating as a lean virtual CRO, the company offers clinical development planning, protocol design, site selection and activation, regulatory submissions, patient recruitment, and clinical monitoring. The team has experience across solid tumours, haematological malignancies, checkpoint inhibitors, and cell therapy programmes including CAR-T.

Clinical trial site management and patient recruitment services

4 Medical Clinical Solutions (4MCS) is a UK-based clinical research organisation providing dedicated clinical trial site and patient recruitment services for pharmaceutical and medical research studies. The company supports Phase Ib to Phase IV clinical trials through site management, feasibility assessment and access to patient populations across multiple therapeutic areas. 4MCS works with pharmaceutical and research partners to deliver clinical studies and real-world evidence generation from its research facilities in the UK.