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Last Updated: 06/06/2026

Quell Therapeutics

London
Founded 2019
Engineered T-regulatory cell therapies for immune-mediated diseases

Quell Therapeutics is a clinical-stage UK biotech developing engineered T-regulatory (Treg) cell therapies for immune-mediated diseases, using its proprietary technology to engineer Tregs with enhanced persistence and potency.

Its lead candidate QEL-001 is in the Phase 1/2 LIBERATE trial for liver transplant tolerance.

A 2023 AstraZeneca collaboration worth up to $2 billion covers CAR-Treg programs in type 1 diabetes and inflammatory bowel disease, with both programs triggering $10 million milestone payments in 2024–25.