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Last Updated: 05/06/2026

Resolution Therapeutics

Edinburgh
Founded 2020
Engineered macrophage cell therapy for inflammatory and fibrotic disease

Resolution Therapeutics is a clinical-stage biotech developing regenerative macrophage therapies for inflammatory and fibrotic diseases.

Its platform harnesses the tissue-repairing properties of macrophages, engineering them to deliver anti-fibrotic and anti-inflammatory effects at sites of organ damage.

The lead programme, RTX001, is an autologous engineered macrophage therapy in a Phase I/II trial for end-stage liver disease.

The pipeline extends into graft-versus-host disease and lung fibrosis. The company has raised £73.5 million, backed by Syncona.